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OCR: Froid This 'trapped' iodide is oxidised by the th yrosine peroxidase enzyme (TPO) and linked to molecules in thyroglobulin to form sines monoiodotyrosines (MIT) and diiodotyr active. The(DIT), neither of which are metabolically oglobulin iodotyrosines are formed within the thy follicular molecules (which are synthesised by the cells and secreted into the lumen).